clinical update publication
New Technology Offers Patients Nonsurgical Options

Nationwide trends moving patients away from cardiac surgery can be attributed directly to improved interventional technologies and breakthrough interventional catheterization research, both of which have allowed new populations of heart disease patients to be treated by intervention. Most significant in recent years was the 2003 FDA approval and wide-market release of the drug-eluting stent, the demand for which has not slowed since its April 2003 approval.

“The drug-eluting stent is bringing patient populations into the catheterization laboratories that we were once considered surgical cases,” stated Charles DeBerardinis, DO, Assistant Director, Adult Cardiac Catheterization Laboratory, Deborah Heart and Lung Center. “By drastically reducing restenosis risk, this stent has allowed us to treat patients that were once taken directly to surgery. For example, patients with left main artery disease were not considered interventional catheterization candidates because of, among other factors, the possibility of restenosis in that vessel, potentially leading to serious long-term complications. Now, these patients can be treated successfully with intervention, with decreased risk of restenosis.”

Not only has this revolutionary technology enabled cardiologists to keep their patients out of the operating room, but public awareness of the device (created undoubtedly by the publicity and media attention the drug-eluting stent has received) has also prompted more patients to ask about intervention during visits with their physicians.

Certainly patients are asking for this. In fact, patient demand for intervention is equal to, or greater, than the demand from referring physicians. That is to be expected - anyone needing treatment for heart disease would, if the outcomes were comparable, opt for a tiny incision over an invasive surgery. We’re pleased to offer this option to the patients who are candidates for it.

Acute Myocardial Infarction
While the drug-eluting stent has the highest level of public awareness, it is not the only option that has allowed more patients to be fully treated by intervention. According to Christine Gasperetti, MD, Attending Interventional Cardiologist, Deborah Heart and Lung Center, recent research has proven that, during acute myocardial infarction, angioplasty may be more effective in some patients than high doses of clot-busting drugs. This finding has introduced an entirely new population to catheterization laboratories.

“Once treated traditionally with clot-busters, recent research has indicated that some patients, during or up to two hours after the start of an acute myocardial infarction, suffer less heart muscle damage when taken directly for angioplasty,” explained Dr. Gasperetti. “This option is also particularly valuable for older patients who might have contraindications for clot-busters.”

Post-bypass
Because surgical techniques and technologies have improved over decades, patients are living many more years after bypass. While this seems an ideal outcome, it also brings more patients back to the hospital, many years later, with graft occlusions. Many of these patients have reached ages where surgery is then contraindicated, or return with comorbidities that make surgery a higher risk treatment option.

“While Deborah’s surgeons are highly skilled in treating even the oldest patient populations, and successfully treat many of the region’s highest-risk patients, there are times when patients are contraindicated to undergo another bypass surgery without high risk,” explained Dr. Gasperetti. “For these patients, intervention has become a more acceptable and effective option to treat graft occlusions. In addition to general refinements and improvements that have been made to the technology over the years, Deborah offers intervention with distal embolization protection devices, which, during angioplasty procedures, protect plaque from traveling through the artery and causing infarction downstream from the graft stenosis. This technology is particularly successful in treating disease in older grafts.”

Patient-Focused Treatment
Despite intense patient and physician demand, and despite rapid advances in the intervention field, there are still patients for whom surgery is the best option.

There are patients who can’t be treated by catheter-based intervention. There are patients whose diseased arteries are not physically reachable by catheter, patients with multiple stenoses that would require several interventional procedures, and some patients with anatomy that is simply not amenable to intervention. While interventions are drastically increasing, surgery is still – and will be for the foreseeable future – the best option for some patients.

However, with the number of advances in technology and research, and the ongoing evaluation and addition of new technology to Deborah’s arsenal of both surgical and interventional treatment options, Deborah’s cardiologists will be equipped to ensure that each patient is individually evaluated and receives the most appropriate treatment for his or her specific condition.

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